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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Surface-anchored microbial enzyme-responsive solid lipid nanoparticles enabling colonic budesonide release for ulcerative colitis treatment

Fig. 6

Histological evaluation of colon tissue and the expression levels of representative factors of inflammation in the colon for each group. (A) Histological evaluation of colon tissue in each group (the red box shows the irregular morphology of the colon). The tissue images are shown at 40 × magnification. Average MPO activity and proinflammatory cytokine expression in the healthy group, colitis group, free BUD-treated group, SLN-BUD-treated group and SLN-BUD-2L-treated group: MPO assay (B); TNF-α levels (C) and IL-6 levels (D). All data are expressed as the means ± SDs (n = 6; *p < 0.05, **p < 0.01, ***p < 0.005, ****p < 0.001)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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