Fig. 3
From: Cooperative phototherapy based on bimodal imaging guidance for the treatment of uveal melanoma
A Time-dependent 1O2 generation of FTCPNPs was irradiated by 660 nm laser (5 mW/cm2). The concentration of Ce6 was 10 µg/mL. B, C Following different treatments (660 nm laser dose: 5 mW/cm2, 3 min), DCFH-DA staining in C918 cells was observed by CLSM, and flow cytometry analysis was used to quantify ROS production. Scale bar: 100 μm. D ARPE-19 and C918 cell viability after co-incubated with FTCPNPs (n = 5). E C918 cell viability after various treatments (808 nm, 2.0 W/cm2, 5 min for PTT and 660 nm, 5 mW/cm2, 3 min for PDT). F After various treatments, CLSM images of C918 cells were stained with CAM and PI. Scale bar: 100 μm. G, H C918 cell apoptosis was analyzed by flow cytometry and quantitative analysis of each group