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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Cooperative phototherapy based on bimodal imaging guidance for the treatment of uveal melanoma

Fig. 5

A The volcano map showed gene expression changes in C918 cells after treatment. B Heat map showed the differentially expressed genes after clustering between the control group and the PTT/PDT group. C KEGG analysis showed significantly enriched pathway changes after co-treatment, such as autophagy, apoptosis, and thermogenesis, etc. D GO showed changes in biological function, such as apoptosis and mitochondrial function, after synergistic therapy. E GSEA showed enriched Necroptosis and ATPase activity pathways. F Heat map showed the differential changes in apoptosis-related genes after synergistic treatment. G Western-blot showed the changes of apoptosis-related genes Bcl-2 and Bax

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