Fig. 6
From: Cooperative phototherapy based on bimodal imaging guidance for the treatment of uveal melanoma
A The T1 signal intensity and FTCPNPs concentration (0.0375, 0.075, 0.15, 0.3, 0.6 and 1.2 mg/mL) were linearly related. T1-weighted MRI images of FTCPNPs aqueous solution at various concentrations were shown in the inset. B After intravenous injection of FTCPNPs, time-dependent T1-weighted MRI images of C918-tumor-bearing mice were obtained and C the intensity of the corresponding MR signal (n = 3). D The linear correlation of PA signal intensity and the concentration of FTCPNPs (0.25, 0.5, 0.75, 1.0 and 1.25 mg/mL) and the PAI images of FTCPNPs aqueous solution at various concentrations were shown in the inset (λex = 690 nm). E Tumor-region PAI images in vivo and F the corresponding signal intensity values (n = 3). G After intravenous injection of FTCPNPs, FL images of C918-tumor-bearing mice were obtained. H Ex vivo FL images of major organs and tumor dissected from mice 48 h after FTCPNPs injection. I Analysis of the quantitative bio-distribution of FTCPNPs as measured by the average FL signal intensity of organs and tumors in mice (n = 3). J Quantitative analysis of FL signal intensity with time in the tumor region (n = 3)