Fig. 3From: CRISPR-Cas13a-powered electrochemical biosensor for the detection of the L452R mutation in clinical samples of SARS-CoV-2 variantsOptimization of crRNAsFluorescence analysis of crRNAs introduced with (a) a single mismatch at different sites targeting the SARS-CoV-2 wild-type RNA template and (b) a dual mismatch at different sites targeting the BA.2 and BA. 5 RNA templates(crRNA, CRISPR RNA)Back to article page