Fig. 4

(a) In vivo PAI of the visceral mice and tumor sites under 1064 nm lasers after intravenous injection at different time intervals (0, 3, 6, 9, 12, 24, and 36 h). (b) The PAI imaging intensity at different time intervals (0, 3, 6, 9, 12, 24, and 36 h). (c) In vitro CT images of UGs@PEG with different concentrations (0, 1.5, 3, 6, 12, and 24 mg mL^− 1) and CT Hounsfield unit (HU) plot. (d) In vivo CT images for 24 h. (e) The CT value of tumor-bearing mice before and after intravenous (i.v.) and intratumoral (i.t.) injections of UGs@PEG. (f) In vivo representative photothermal images of tumor-bearing mice under 1064 nm laser irradiation for 10 min after injection with PBS and UGs@PEG. (g) The corresponding heating curves in the tumor regions of mice treated with PBS and UGs@PEG