Fig. 2From: Metabolomic investigation of urinary extracellular vesicles for early detection and screening of lung cancerCharacterization of EVs isolated from lung cancer patients and healthy doners. (a) Western blotting analysis of EV protein markers (CD63, CD9, CD81) and lung cancer-specific signature (LRG1) carried by urinary EVs. UMOD used as a negative control. An equal protein amount of 2 µg was loaded for all samples. (b) The distribution profiles of particle size from lung cancer at different stages, and healthy control in (c). (d) Characterizations of particle size from the lung cancer at different stages and control group, indicating that EVs are more abundant in patients with lung cancer. (e) Transmission Electron microscopy (TEM) analysis showing typica cup shape morphology of EVs from a lung cancer patient and (f) a healthy donerBack to article page