Fig. 4

Effects of stem cell transplantation system on cellular oxygenation, survival, and paracrine effects under hypoxic conditions. A Oxygen release kinetics in stem cell transplantation systems with different microsphere contents within three weeks (n = 3). B The situation of viable cells within three weeks of culture in stem cell transplantation system with different microsphere content (n = 3). C Changes of paracrine-related growth factor protein content with or without oxygen release after 21 days of culture under 1% oxygen condition (n = 3). D Changes in paracrine-related growth factor mRNA expression levels with or without oxygen release after 21 days of culture under 1% oxygen condition (n = 3). ***P < 0.001