A liposomal carbohydrate vaccine, adjuvanted with an NKT cell agonist, induces rapid and enhanced immune responses and antibody class switching

Table 1 Formulation and characterization of liposomal vaccines

	Composition (molar ratio)	Antigen/Adjuvant	Size (nm)	PDI	Zeta potential (mV)
LP-4S	DPPC:CH = 4:1	4S	236.8 ± 0.46	0.361 ± 0.017	-21.8 ± 0.8
NLP	DOPC:CH = 2:1	Phy-P	99.3 ± 0.7	0.184 ± 0.023	-11.7 ± 1.55
NLP-4S	DOPC:CH = 2:1	4S	126.6 ± 1.1	0.157 ± 0.006	-19.2 ± 1.84
NLP-4S-PBS57	DOPC:CH = 2:1	4S + PBS57	152.9 ± 6.9	0.267 ± 0.014	-22.5 ± 1.97

ISSN: 1477-3155