Fig. 2

TME-triggered cascade effect of SG@M. A Schematic illustration of Fenton-like reaction (Created with BioRender.com). B UV–vis absorption spectra of the degradation properties of SG@M triggered by H⁺ and GSH and the corresponding photos of solution (inset). C Relative GSH content at different time points after the reaction with different NPs (n = 3). D Mn²⁺ release from SG@M at pH 7.2, pH 6.5 with or without GSH buffer solution after 24 h of incubation and E 2 h of incubation. F Drug release from SG@M at pH 7.2, pH 6.5 with or without GSH buffer solution after 24 h of incubation. G UV–vis absorption spectra of MB degradation in acid (pH 6.5) with different concentrations of GSH and H different concentrations of SG@M. I Photos of the reactions between (a) H₂O₂, (b) SG and H₂O₂, (c) SG@M, (d) SG@M and H₂O₂, respectively. J The O₂ generation ability of SG@M by measuring RDPP fluorescence at 615 nm. K Dissolved O₂ concentration in different solutions