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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: A hybrid nanopharmaceutical for specific-amplifying oxidative stress to initiate a cascade of catalytic therapy for pancreatic cancer

Fig. 4

Antitumor therapy of SG@M in vitro. A Intracellular GSH level after different treatments (n = 3). B Cell viability of PANC‒1cells with different treatments (n = 3). C Flow cytometry analysis of cell apoptosis after different treatments (200 μg/mL SG or SG@M, equivalent to 22.18 μg/mL GAL). D Western blot analyses of BAX and Bcl-2 protein levels in PANC-1 cells after different treatments. E Molecular mechanism of cell growth arrest and apoptosis triggered by ROS (Created with www.BioRender.com). F Flow cytometry analysis of cell cycle distribution and G Western blot analyses of Cyclin B1 protein levels of PANC-1 cells in different treatment groups

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