Fig. 6

Ability of the semiconducting polymer nanoparticles to evaluate the severity of acute pancreatitis. (a) The reaction mechanism by which the ROS content was monitored by CL in vivo. (b) Chemiluminescence imaging of mice at different time points (blue dotted line: liver, red dotted line: pancreas, n = 3). (c) Corresponding quantification of the chemiluminescence intensity in the liver areas in the control group. (d-e) Corresponding quantification of the chemiluminescence intensity in the pancreas and liver areas in the MAP and SAP groups. (f) Ratio of the chemiluminescence intensity in the liver: MAP/control and SAP/control. (g) H&E-staining images of the pancreas and other organs, including the heart, liver, kidney and lung, in mice of the three groups. (Data represent means ± SDs, **p < 0.01, ***p < 0.001.)