Fig. 5

ARNP inhibits the growth of primary tumors in vivo. (A) Tumor volume of the primary tumor recorded every two days in mice. (B) Tumor weights and (C) tumor images of primary tumors in mice administered different treatments. (D) Representative images of H&E staining and (E) Ki67 immunohistochemical staining of primary tumors from different groups (scale bar represents 20 μm). All data are presented as the mean ± SD (n = 6). *p < 0.05, **p < 0.01