Fig. 5

A Schematic diagram of rabbit bone regeneration experiment; B Flow chart of scaffold implantation in rabbit bone defect; C Micro-CT reconstruction images of femoral defect; D Coronal and transverse micro-CT reconstruction images of new bone at defect site; E Volume fraction of new bone in the area of the bone defect (BV/TV); F–I Trabecular number (Tb.N), trabecular thickness (Tb.Th), trabecular separation (Tb.Sp) and cortical bone thickness (Ct.Th) of new bone in the defect area by micro-CT quantitative analysis; J H&E staining of new bone tissue slices. *p < 0.05, **p < 0.01, ***p < 0.001