Fig. 4
From: Oncogene-targeting nanoprobes for early imaging detection of tumor
Reprinted with permission from ref [97, 98]
(A) Schematic illustration of steps involved in preparation of MFR-AS1411 [97]; (B) Radionuclide images of C6 tumors at 1, 6, and 24Â h after injecting MFR-AS1411 and MFR-AS1411mt [97]; (C) MR images of tumor-bearing mice after injection of MFR-AS1411 [97]; (D) Schematic illustration of cancer cell membrane camouflaged nanoprobe (DMSN-DP@CM) for catalytic ratiometric PAI of miRNA detection in living mice [98]. (E) In vivo fluorescent images of MCF-7 tumor bearing mice were detected after injecting DMSN-DP@CM solution into the tail vein [98]. (F) PA images of MCF-7 tumor bearing mice treated with DMSN-DP@CM with different time points [98].