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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: Oral membrane-biomimetic nanoparticles for enhanced endocytosis and regulation of tumor-associated macrophage

Fig. 1

Optimum ratio of a combination of LU and SL, as determined by cell viability and qPCR assays. (A) The cytotoxicity (IC50) and combination index (CI) in 4T1 cells with different ratios of free LU/SL. (B-F) The relative mRNA expression of the macrophage-associated markers TNF-α, iNOS, TGF-β1, MR, and CCL2 by qPCR assay after LU/SL treatment in Raw264.7 cells. Mean ± SD, n = 3; *P < 0.05, **P < 0.01, ***P < 0.005. Abbreviations: LU/SL, luteolin and silibinin; SD, standard deviation; qPCR, quantitative polymerase chain reaction

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