Fig. 2

The characterizations and self-assembly behavior of 2-BP/CPT-PLNs. A Hydrodynamic size distribution and photograph of 2-BP/CPT-PLNs. The physical picture of the 2-BP/CPT-PLNs formulation was inserted. B TEM images of 2-BP/CPT-PLNs. C Particle size changes of 2-BP/CPT-PLNs in PBS, or medium in the presence or absence of FBS (n = 3). D Particle size and count rate changes of 2-BP/CPT-PLNs in various concentrations of NaCl solutions (n = 3). E, F Fluorescence spectra, particle size, and count rate changes of 2-BP/CPT-PLNs in aqueous solutions of SDS (n = 3). G Schematic illustration of self-assembly driven forces and GSH-triggered drug release of 2-BP/CPT-PLNs. H Particle size distribution and cumulative CPT release profiles of 2-BP/CPT-PLNs in PBS (10 mM, pH 7.4) solutions in the absence or presence of GSH (2 µM, 2 mM, 10 mM) (n = 3). Data were represented as mean ± SD