Fig. 6

2-BP/CPT-PLNs prevented B16-F10 melanoma metastasis in vivo. A Schedule and timeline for constructing the B16-F10 tumor metastasis model and dissecting lungs and livers from mice after treatments with various formulations. B The images of the excised lungs. The red dotted circles represented melanoma metastasis nudes within the lungs. C The digital analysis of lung metastasis nudes (n = 4). D H&E staining of lung and liver slides. The red arrows represented the tiny metastasis nudes within livers. Bar: 100 μm. *p < 0.05, **p < 0.01 or ***p < 0.001 represented significance