Fig. 2

hucMSC-Ex repairs IBD in mice. A, Changes in body weight of mice; B, Assessment of DAI score of mice; C, Gross view of the colon of mice; D, H&E staining of the colon (scale bar = 50 μm); E, Gross view of the spleen of mice; F, H&E staining of spleen tissue of mice (scale bar = 100 μm); G, Western blot analysis of the expression level of PCNA; H, Western blot analysis of the expression level of intestinal tight junction related molecules in colon tissue; I, QRT-PCR analysis of inflammatory factors mRNA expression in mice colon tissue. (Data are presented as mean ± SD by student t-test. (^*P < 0.05; ^**P < 0.01; ^***P < 0.001)