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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Human umbilical cord mesenchymal stem cells derived exosome shuttling mir-129-5p attenuates inflammatory bowel disease by inhibiting ferroptosis

Fig. 5

miR-129-5p is highly expressed in hucMSC-Ex. A, small RNA sequencing results of hucMSC-Ex; B, The binding site of miR-129-5p to the 3’-UTR of ACSL4 mRNA sequence; C, The expression of miR-129-5p in HCoEpiC co-incubated with hucMSC-Ex; D, Expression level of ACSL4 mRNA after transfection of miR-129-5p mimics and inhibitors; E, Detection of transfection efficiency of miR-129-5p mimics and inhibitors; F, Dual-luciferase reporter gene of the targeting relationship between miR-129-5p and ACSL4. Data are presented as mean ± SD by student t-test. *P < 0.05; **P < 0.01; ***P < 0.001

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