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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Human umbilical cord mesenchymal stem cells derived exosome shuttling mir-129-5p attenuates inflammatory bowel disease by inhibiting ferroptosis

Fig. 7

Repair of DSS-induced IBD by hucMSC-Ex transfected with miR-129-5p mimics and inhibitors. A, Changes in body weight of mice; B, Assessment of DAI score of mice; C, Gross view of mice colon; D, Gross view of mice spleen; E, Western blot analysis of the expression level of PCNA in mice; F, H&E staining of mice colon (scale bar =50 μm) and spleen (scale bar = 200 μm); G, Expression levels of inflammatory factors in mice intestinal tissue. Data are presented as mean ± SD. *P < 0.05; **P < 0.01; ***P < 0.001

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