Fig. 5

Intrinsic signal pathways analysis. (A) Western blot analysis of the protein expression of Bax, Bcl-2, Cyt c, and cleaved caspase-3 in 4T1 cells treated at different conditions. (B, C, D and E) The corresponding semi-quantitative analysis of Western blot band gray values of Bax, Bcl-2, Cyt c, and cleaved caspase-3 by ImageJ. (F) Schematic diagram of DNA origami nanovehicle inducing apoptosis via signaling pathways in vitro. The data are presented as the mean ± SD (n = 3). ns: not significant. *p < 0.05, **p < 0.01, ***p < 0.001