Fig. 7

Therapeutic effects of the DNA origami-based nanovehicle in vivo. (A) Schematic timeline illustration of animal therapy. (B) Tumor volume of 4T1 tumor-bearing mice after the specified treatments. (C) Photographs of tumor tissues removed from groups treated with different formulations after 14 d. (D) Ex vivo tumor weights of each group weights at the end of the study (day 14). (E) Body weight curves of 4T1 tumor-bearing mice for each group. (F) Representative images of H&E, TUNEL, and Ki67 immunostaining of tumor tissues from different groups after various treatments. (scale bar = 100 μm). The data are presented as the mean ± SD (n = 5). **p < 0.01, ***p < 0.001