Fig. 3

ADSC-Exos accelerated diabetic hindlimb ischemia (HLI) repair. a Flow chart for diabetic HLI model construction. b Representative image of blood perfusion in ischemic limbs. c Quantification of blood reperfusion ratio in four groups (n = 5, **p < 0.01, ***p < 0.001, ###p < 0.001 versus PBS). d Quantification of limb motor score (n = 5, *p < 0.05, #p < 0.05 versus PBS). e Quantification of limb salvage score (n = 5). f Schematic of ADSC-Exos therapy on diabetic HLI