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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Exosomal miR-125b-5p derived from adipose-derived mesenchymal stem cells enhance diabetic hindlimb ischemia repair via targeting alkaline ceramidase 2

Fig. 6

miR-125b regulated the proliferation and migration of C2C12 cells. a The miR-125b-5p expression in C2C12 cells treated with miR-125b-5p mimic/ inhibitor. b Western blotting analysis of AMPK and bcl-2 protein expression in C2C12 cells in four groups. c EdU assay of the proliferation rate of C2C12 cells in each group (Scale bar: 50 μm). d Qualification analysis of the proliferation rate (n = 5). e Images of migrated cells in each group (n = 5, scale bar: 50 μm). f Quantitative analysis of the migration rate of C2C12 cells. g Images depicted at 24 h after scratch (Scale bar: 50 μm). h Qualification analysis of the wound healing rate (n = 5). *p < 0.05, **p < 0.01, ***p < 0.001

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