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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Metal-organic framework-encapsulated dihydroartemisinin nanoparticles induces apoptotic cell death in ovarian cancer by blocking ROMO1-mediated ROS production

Fig. 2

ZIF-DHA displayed the suppression of cell growth in ovarian cancer cells. (A-C) The intracellular uptake of ZIF-DHA-MR was detected using flow cytometry. (D-H) CCK-8 cell viability assay was used to explore the effects of ZIF-DHA on ovarian epithelial cells IOSE80 and several ovarian cancer cells, SKOV3, A2780, OVCAR3 and TOV112D. (I-K) The colony formation assay was used to evaluate the functional roles of ZIF-DHA on cell growth in ovarian cancer cells SKOV3 and A2780. The data in graphs represent mean ± SD. **p < 0.01

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