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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Metal-organic framework-encapsulated dihydroartemisinin nanoparticles induces apoptotic cell death in ovarian cancer by blocking ROMO1-mediated ROS production

Fig. 3

The altered pathways and molecules in response to ZIF-DHA identified by 4D-FastDIA. (A) The heatmap indicated the differentially expressed proteins in ZIF-DHA-treated SKOV3 and A2780 cells. (B) The graphs indicated the differentially expressed proteins in ZIF-DHA-treated SKOV3 and A2780 cells. (C-D) The co-differentially expressed proteins in ZIF-DHA-treated SKOV3 and A2780 cells. (E) mitochondria were labeled by the mito-tracker. The location of ZIF-DHA-MR were observed with laser confocal microscopy. (F-H) After ZIF-DHA treatment, GSEA indicated several biological pathways associated with ROMO1 expression

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Journal of Nanobiotechnology

ISSN: 1477-3155

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