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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Anti-Her2 affibody-decorated arsenene nanosheets induce ferroptosis through depleting intracellular GSH to overcome cisplatin resistance

Fig. 6

Therapeutic efficacy of Her2-ANs in vivo. (A) In vivo tumor treatment schedule. (B) Tumor growth curves of different groups. (C) Tumor photos after various treatments. (D) Tumor inhibition rates of different groups. (Values are presented as means ± sd, n = 6, *P < 0.05, **P < 0.01.) (E) The final weight of tumor tissues extracted from mice after different treatments. (Values are presented as means ± sd, n = 6, *P < 0.05, **P < 0.01.) (F) Body weight changes in mice within 2 weeks after different treatments. (G, H) Flow cytometry analysis of the production of ROS (G) and lipid peroxide (H) in the tumor of different groups. (I) HE, immunohistochemical and immunofluorescence analysis of tumor slices obtained from different groups. Scale bar: 50 μm

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