Fig. 6

Oral EUP-SeNP altered the microbial composition of the colon in DSS-treated mice. A Veen diagram of colonic microorganisms OTUs. B ACE index. C Chao1 index. D Shannon index. E Principal coordinates analysis (PCoA) of colonic microorganisms. F Non-metric multi-dimensional scaling (NMDS) of colonic microorganisms. G–K Colon microbiota composition at Phlyum, Class, Order, Family and Genus level. L Changes in the abundance of some beneficial and harmful bacteria in colon tissue. Data are means ± SEM. (n = 5) “*”P < 0.05, “**”P < 0.01, “***”P < 0.001 and “****”P < 0.0001 by one-way ANOVA with Bonferroni’s multiple comparisons test. “#”P < 0.05, “##”P < 0.01, “###”P < 0.001 and “####”P < 0.0001 by one-way ANOVA with Bonferroni’s multiple comparisons test. “*” represents the significance between the control group and the DSS model group; “#” represents the significance between the DSS model group and the treatment group