Fig. 7

Oral EUP-SeNP does not cause damage to body. We simulated the short-term and long-term toxic effects of EUP-SeNP, administered orally for 7 days and 30 days. A Seven-day weight change (n = 5); B Oral administration of EUP-SeNP serum AST for 7 days; C Oral administration of EUP-SeNP serum ALT for 7 days; D Thirty-day weight change (n = 5); E Oral administration of EUP-SeNP serum AST for thirty days; F Oral administration of EUP-SeNP serum ALT for 30 days; G Morphology of organs at necropsy, scale bar is 1 cm. H H&E staining of heart, liver, spleen, lung, kidney and colon after 7 and 30 days of oral EUP-SeNP, scale bar is 100 μm