Fig. 2
From: Advances in PD-1 signaling inhibition-based nano-delivery systems for tumor therapy
Copyright 2021, Wiley
a Schematic diagram of Gd-Au-DENPs synthesis. b Mechanism of anti-tumor immunotherapy with PD-1 siRNA. c In vivo 3D reconstructed micro-CT images (with pseudocolor image of tumor sites, indicated by red dashed squares). d In vivo T1-weighted pseudocolour MR images (tumors is shown as red dashed ovals). e Relative PD-1 mRNA levels in T cells after different treatments determined by RT-qPCR. Reproduced with permission from [66].