Fig. 3From: Advances in PD-1 signaling inhibition-based nano-delivery systems for tumor therapyCopyright 2019, ACSa Schematic diagram of the preparation of siRNA@PLGA nanoparticles and their functions in vivo. b Silencing of PD-1 expression on anti-CD3/CD28-stimulated CD8+T cells by siRNA@PLGA was demonstrated by Western blotting. c In vitro silencing of PD-L1 expression on MC38 cells by siRNA@PLGA was demonstrated by Western blotting. Reproduced with permission from [95].Back to article page