Fig. 4

a Schematic of dual immunotherapy nanoparticles (DINP) simultaneously binding to PD1 and OX40 to activate more T cells. b Schematic diagram of the preparation of DINP. c Representative image depicting DINP (Scale bar: 100 nm). d Scatter plot with median line of relative abundance of T cells, CD8⁺T cells and CD4⁺FOXP3⁺ regulatory T cells (Treg) subpopulations in tumors from animals receiving different immunotherapy regimens, as assessed by flow cytometry analysis. Reproduced with permission from [97].