Fig. 9

a Schematic diagram of the preparation of PLGA nanoparticles loaded with HAuNS and APP. b Schematic diagram of the experimental principle. c Primary tumor volumes in 4T1 model mice after various treatments (n = 7). d Distant tumor volumes in 4T1 model mice after various treatments (n = 7). e Weight of primary and distant tumors measured at the end of treatment. f Number of metastatic tumor nodules in lung tissues of BALB/c mice bearing CT26 lung metastases after treatment with dual immunotherapy. g Primary tumor volumes curves in mice after 3 weeks of treatment and recurrent tumor volumes curves after surgery or PTA (n = 5–10). h The rechallenged tumor volumes curves of mice after 3 weeks of treatment (n = 5–10). Reproduced with permission from [110].