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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: 3-Bromopyruvate-loaded bismuth sulfide nanospheres improve cancer treatment by synergizing radiotherapy with modulation of tumor metabolism

Fig. 6

Anti-tumor efficacy in vivo. (a) Schematic illustration of the Bi2S3-3BP-based RT process. (b) Representative photographs of 4T1 tumor-bearing mice of six groups during the 14 d period. (c) Photographs of tumors dissected from mice of six groups after various treatments. (d) Tumor growth curves of six groups after various treatments. (n = 5). (e) Body-weight curves of six groups during the observation period. (n = 5). (f) Weight of tumors at 14 d post various treatments and tumor growth inhibition rate (n = 5). (g) H&E, TUNEL and PCNA staining of tumors from 4T1 tumor-bearing mice after various treatments. (h) Mean fluorescence intensity semiquantitative analysis of PCNA and TUNEL (n = 5). *P < 0.05, **P < 0.01, ***P < 0.001

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