Fig. 5
From: Next-generation nanomaterials: advancing ocular anti-inflammatory drug therapy
Adapted from Ref. [218] with permission from Elsevier
The electrospinning process for the creation of polymer-free and free-standing acyclovir/cyclodextrin nanofibers, notable for their exceptional histocompatibility and facilitation of drug release in the treatment of viral keratitis. A Chemical structures of (a) HP-βCD, (b) PVP, and (c) acyclovir are presented, (d-e) alongside schematic diagrams demonstrating their interrelationships. B Experimental data confirms the solubility of acyclovir/HP-βCD nanofibers and acyclovir/PVP nanofibers in an artificial saliva environment.