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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: “Dual sensitive supramolecular curcumin nanoparticles” in “advanced yeast particles” mediate macrophage reprogramming, ROS scavenging and inflammation resolution for ulcerative colitis treatment

Fig. 3

Cell internalization profiles of NPs: (A) Qualitative analysis of uptake by RAW264.7 macrophages: (B) Quantitative measurement of CS-CUR NPs uptake by RAW264.7 macrophages (incubation times of 0, 0.25, 0.5, 1, 2, and 4 h; CUR concentration of 32 µg/mL). (C) Quantitative test of Man-CUR NPs uptake by RAW264.7 macrophages (4 h, different CUR concentrations 2, 4, 8, 16, and 32 µg/mL). (D) Quantitative uptake measurement by RAW264.7 macrophages treated with different formulations (4 h, CUR concentration of 32 µg/mL). (E) Quantitative result uptake by RAW264.7 macrophages incubated with CUR NPs and Man-CUR NPs with or without the pretreatment of D-Man. Data are shown as mean ± SD (n = 3). ⁎p < 0.05, ⁎⁎p < 0.01

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