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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: “Dual sensitive supramolecular curcumin nanoparticles” in “advanced yeast particles” mediate macrophage reprogramming, ROS scavenging and inflammation resolution for ulcerative colitis treatment

Fig. 7

Anti-inflammatory and antioxidant effects of Man-CUR NYPs on UC mice in vivo: (A) The expression levels of TNF-α, IL-1β, IL-4 and IL-10 in the colons, measured by ELISA assays. (B) Western blotting results and histogram analysis of the influence of each group on the changes of TLR4, MyD88 and NF-κB p65 protein expression in colon. (C) The expression levels of MPO, SOD and MDA in the colons, measured by ELISA assays. (D) Western blotting results and histogram analysis of the influence of each group on the changes of HO-1 and Nrf-2 protein expression in colon. (E) Representative IHC staining of Arg-1, CD206, CD86 and iNOS in the colon tissues. (F) Western blotting results and histogram analysis of the influence of each group on the changes of Arg-1 and iNOS protein expression in colon. Data are mean ± SD (n = 6). *p < 0.05; **p < 0.01

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Journal of Nanobiotechnology

ISSN: 1477-3155

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