Skip to main content
Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: CAFs targeted ultrasound-responsive nanodroplets loaded V9302 and GLULsiRNA to inhibit melanoma growth via glutamine metabolic reprogramming and tumor microenvironment remodeling

Fig. 2

Preparation and characterization of the nanodroplets. (A) Preparation of the nanodroplets. (B) Fluorescence microscope diagram of FH-V9302-siGLUL-NDs. Scale bars: 10 μm. (C) Transmission electron microscopy (TEM) of FH-V9302-siGLUL-NDs at a volume ratio of 1:20 ratio (siGLUL: nanodroplets). Scale bars: 200 nm. (D) FH-V9302-siGLUL-NDs size distribution. (E) Drug release of FH-V9302-siGLUL-NDs with or without ultrasound stimulation (0.5 W/cm2, 60 s, 1.0 MHz). (F) US imaging in vitro. (G) US imaging in vivo. The red circle indicates the site of the tumor. All statistical data are expressed as means ± SD (n = 3)

Back to article page