Fig. 4

Targeted ability of FH-NDs. (A&C) Fluorescence microscope diagram of the targeted ability of FH-NDs. Scale bars: 30 μm. (B&D) Fluorescence microscope diagram of the targeted ability of NDs. Scale bars: 30 μm. (E-H) Flow cytometry measured the targeted ability of NDs and FH-NDs in CAFs and NIH/3T3 cells after incubation for one hour. (I) Fluorescence micrograph of the targeting ability of nanodroplets under co-culture conditions of CAFs with B16F10. Scale bars: 100 μm. (J) Targeting ability and accumulation of FH-NDs and NDs in tumor 4 h after injection of Dil-labelled nanodroplets. Scale bar: 200 μm. (K) Targeting ability of FH-NDs and NDs in mice 4 h after injection of Dil-labelled nanodroplets. (L) Quantitative analysis of targeting ability of FH-NDs and NDs in mice. **p < 0.01(t-test). All statistical data are expressed as means ± SD (n = 3)