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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: CAFs targeted ultrasound-responsive nanodroplets loaded V9302 and GLULsiRNA to inhibit melanoma growth via glutamine metabolic reprogramming and tumor microenvironment remodeling

Fig. 7

Inhibition of ECM and CAFs morphology after various treatments (A) Western blot analysis of collagen I and α-SMA after 48 h of CAFs treated with different elements containing siGLUL. (B) Quantitative analysis of collagen I expression in CAFs. (C) Quantitative analysis of α-SMA expression in CAFs. (D) Fluorescence microscope diagram of CAFs morphology 24 h after various treatments. Scale bar: 50 μm. *p < 0.05, ***p < 0.001 (ANOVA test). All statistical data are expressed as means ± SD (n = 3)

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