Fig. 7From: CAFs targeted ultrasound-responsive nanodroplets loaded V9302 and GLULsiRNA to inhibit melanoma growth via glutamine metabolic reprogramming and tumor microenvironment remodelingInhibition of ECM and CAFs morphology after various treatments (A) Western blot analysis of collagen I and α-SMA after 48 h of CAFs treated with different elements containing siGLUL. (B) Quantitative analysis of collagen I expression in CAFs. (C) Quantitative analysis of α-SMA expression in CAFs. (D) Fluorescence microscope diagram of CAFs morphology 24 h after various treatments. Scale bar: 50 μm. *p < 0.05, ***p < 0.001 (ANOVA test). All statistical data are expressed as means ± SD (n = 3)Back to article page