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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Nanosilicate-functionalized nanofibrous membrane facilitated periodontal regeneration potential by harnessing periodontal ligament cell-mediated osteogenesis and immunomodulation

Fig. 5

Conditioned medium from PDLCs cultured on PCL/LAP nanofibrous membranes inhibits macrophage inflammatory responses. a Schematic illustration of macrophages treated by conditioned medium from PDLCs. b Representative images of macrophages treated with conditioned medium from PDLCs cultured on PCL/LAP nanofibrous membranes. c-f Inflammatory gene (IL-1β, IL-6, TNF-α and IL-10) expression of macrophages treated with conditioned medium from PDLCs cultured on PCL/LAP membranes. g–j Inflammatory cytokines (IL-1β, IL-6, TNF-α and IL-10) of macrophages treated with conditioned medium from PDLCs cultured on PCL/LAP membranes. Scale bar = 30 μm. *P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001

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