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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Nanosilicate-functionalized nanofibrous membrane facilitated periodontal regeneration potential by harnessing periodontal ligament cell-mediated osteogenesis and immunomodulation

Fig. 6

Conditioned medium from PDLCs cultured on PCL/LAP nanofibrous membranes regulates macrophage polarization. a-b Decreased M1 polarization marker (iNOS) gene and increased M2 polarization marker (ARG1) gene levels of macrophages treated with condition medium from PDLCs cultured on PCL/LAP nanofibrous membrane. c Representative images of immunofluorescent staining iNOS levels and ARG1 levels in macrophages treated with conditioned medium from PDLCs cultured on PCL/LAP nanofibrous membranes. Scale bar = 50 μm. *P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001

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