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Fig. 8 | Journal of Nanobiotechnology

Fig. 8

From: Nanosilicate-functionalized nanofibrous membrane facilitated periodontal regeneration potential by harnessing periodontal ligament cell-mediated osteogenesis and immunomodulation

Fig. 8

PCL/LAP nanofibrous membrane promotes rat mandibular periodontal defect regeneration. a Schematic illustration of rat periodontal defect treated with PCL/LAP nanofibrous membrane. b Representative micro-CT reconstructed images of periodontal defects treated with PCL/LAP nanofibrous membranes. c-d BV/TV ratio and BMD of Micro-CT data analysis. e-f Histological quantitative analysis of new bone area and new attachment formation rate. g Histological H&E- and Masson’s trichome-stained sections of rat periodontal defects. NC, new cementum; NP, new periodontal ligaments; NB, new bone. Scale bar = 200 μm. *P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001

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