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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: VEGFR2 targeted microbubble-based ultrasound molecular imaging improving the diagnostic sensitivity of microinvasive cervical cancer

Fig. 5

Representative images of US molecular imaging USMI in identifying cervical cancer. (A) Representative images of superb microvascular imaging (SMI) in different diameters of cervical cancer. (B) Box-and-whisker plot of quantitative parameter of SMI in different diameters. Representative ultrasound images in B-mode (gray) and molecular ultrasound images (color coded) after administrations of MBCon(C) and MBVEGFR2(D). (E) Quantitative analyses of USMI signal intensity about MBCon in tumor and muscle tissues of each group. (F) Quantitative analyses of USMI signal intensity about MBVEGFR2 in tumor and muscle tissues of each group. (G) Box-and-whisker plot of USMI signal intensity on the basis of NID in different diameters of cervical cancer with MBCon or MBVEGFR2 administration. (H) Linear correlation analysis between the NID and CD34-MVD. (* P < 0.05, ** P < 0.01, ns = nonsignificant)

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