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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Nacre-mimetic cerium-doped nano-hydroxyapatite/chitosan layered composite scaffolds regulate bone regeneration via OPG/RANKL signaling pathway

Fig. 5

(a) CCK-8 analysis for control, HA/CS, and CeHA/CS scaffolds; (b) SEM images for HA/CS and CeHA/CS scaffolds adhered by hBMSCs for 12 h; (c) ALP staining and (d) alizarin red staining images of hBMSCs cultivated with control medium and extraction solution of HA/CS and CeHA/CS scaffolds for 7 and 20 days; Quantitative analysis of (e) relative ALP and (f) alizarin red activities of hBMSCs cultivated with control medium and extraction solution of HA/CS and CeHA/CS scaffolds. * P < 0.05, ** P < 0.01

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