From: Cracking the intestinal lymphatic system window utilizing oral delivery vehicles for precise therapy
Targeting cell | Ligands | Receptors/transporters | References |
---|---|---|---|
M cell | Claudin 4 | CPE | |
UEA-1 or AAL | α-1,2 fucosylation | [147] | |
β-glucans | Dectin-1 | ||
FimH (E. coli, Salmonella) | Glycoprotein 2 | ||
Peptide Co-1 or Omph (Yersinia) | C5aR | [152] | |
LPS | TLR-4 | ||
RGD or Mannose | β1 integrins | [153] | |
Lipotechoic Acid | TLR-2 | ||
CKS9 | EGF-A | [156] | |
Enterocyte | Biotin | Biotin receptor | [157] |
Folic acid | Folic acid receptor | [158] | |
Lectin | Lectin receptor | [159] | |
Glycocholic acid | ASBT | ||
Albumin | FcRn | [162] | |
L-valine | Oligopeptide transporter | [163] | |
Vitamin B12 | Vitamin B12 receptor | [164] | |
Dextran | Dextran-binding receptor |