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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: A multifunctional integrated biomimetic spore nanoplatform for successively overcoming oral biological barriers

Fig. 1

Preparation and characterization. SEM and TEM images of (a) spores and (b) SC, respectively. The SEM and TEM images of (c) DS NPs and (d) SC@DS NPs, respectively. (e) The morphologies of DS NPs and SC@DS NPs were investigated after 2 h incubation in SGF. (f) The cumulative DOX and SOR release of DS NPs and SC@DS NPs in SGF. (g) The morphology changes of DS NPs and SC@DS NPs after 4 h incubation in SIF. (h) The cumulative release amount of SOR and DOX in DS NPs and SC@DS NPs groups after being incubated in SIF for 4 h. (i) The release behavior of drugs from DS NPs and SC@DS NPs after being incubated in a buffer with gradually varying pH for over 24 h. (j) The percentage of particles-mucin aggregation formed in simulated mucus solution for different preparations at 37℃

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