Fig. 3

Analyses of the cellular factors involved in BSO@MOF-L-mediated ferroptosis. a Schematic illustration of the ferroptosis mechanism. b Intracellular GSH level and c GPX4 expression of 4T1 cells after treated with BSO, MOF-L, or BSO@MOF-L. Microscopic images of cells after DCFH-DA (d) and BODIPY581/591-C11 (e) staining after treated with BSO, MOF-L, or BSO@MOF-L. Flow cytometry analysis of the 4T1 cells after DCFH-DA f–g and BODIPY581/591-C11 h–i staining with different treatments (n = 3). DCFH-DA, dichlorofluorescein diacetate. * p < 0.05