Fig. 7
ZIF-8-DPSCs promote nerve tissue formation in SCI rats. (A) H&E staining transverse section of injured spinal cord tissue 28 days after injury. Above is the spinal cord at low magnification, with scar tissue and cavity visible in the SCI group, and below is the spinal cord at higher magnification. (B) Spinal cord tissue preserved on day 28 after spinal cord injury. Quantitative analysis of HE sections showed that. (C) The expression of VEGF-a and βIII-tubulin in the Sham, SCI group, GelMA group, DPSCs group and ZIF-8-DPSCs group was analyzed by immunofluorescence. Fluorescence intensity quantification of βIII-tubulin (D) and VEGF-a (E) is given. (F) TSQ fluorescence staining was used to detect Zn2+ in the Sham, SCI group, GelMA group, DPSCs group and ZIF-8-DPSCs group. The white arrow points to cells that overexpress Zn2+. (G) Fluorescence intensity of Zn2+ is quantified. *P < 0.05. **P < 0.01. *** P < 0.001. Data are represented as mean ± SD (n = 6)